SPRI_4591 protein (Streptomyces pristinaespiralis)

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[Homology]

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SPRI_4591

Integration host factor; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (93 aa)

Predicted Functional Partners:

rplS

0.810

rpsT

0.751

rpsO

0.700

SPRI_2155

0.646

rplL

0.602

atpC

0.564

SPRI_4587

0.540

dnaA

0.534

tig

0.534

SPRI_4588

0.530

Your Current Organism:

Streptomyces pristinaespiralis

NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SPRI_2155	SPRI_4591	SPRI_2155	SPRI_4591	Two-component system sensor kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Integration host factor; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.	0.646
SPRI_2155	dnaA	SPRI_2155	SPRI_3784	Two-component system sensor kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.	0.713
SPRI_2155	rpsO	SPRI_2155	SPRI_2166	Two-component system sensor kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.	0.443
SPRI_4587	SPRI_4588	SPRI_4587	SPRI_4588	RNA polymerase sigma factor SigL; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.	RNA polymerase subunit sigma; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.995
SPRI_4587	SPRI_4591	SPRI_4587	SPRI_4591	RNA polymerase sigma factor SigL; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.	Integration host factor; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.	0.540
SPRI_4588	SPRI_4587	SPRI_4588	SPRI_4587	RNA polymerase subunit sigma; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	RNA polymerase sigma factor SigL; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.	0.995
SPRI_4588	SPRI_4591	SPRI_4588	SPRI_4591	RNA polymerase subunit sigma; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Integration host factor; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.	0.530
SPRI_4591	SPRI_2155	SPRI_4591	SPRI_2155	Integration host factor; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.	Two-component system sensor kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.646
SPRI_4591	SPRI_4587	SPRI_4591	SPRI_4587	Integration host factor; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.	RNA polymerase sigma factor SigL; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.	0.540
SPRI_4591	SPRI_4588	SPRI_4591	SPRI_4588	Integration host factor; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.	RNA polymerase subunit sigma; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.530
SPRI_4591	atpC	SPRI_4591	SPRI_2516	Integration host factor; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.	F0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.564
SPRI_4591	dnaA	SPRI_4591	SPRI_3784	Integration host factor; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.	Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.	0.534
SPRI_4591	rplL	SPRI_4591	SPRI_3202	Integration host factor; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.	50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.	0.602
SPRI_4591	rplS	SPRI_4591	SPRI_2258	Integration host factor; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.	50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.810
SPRI_4591	rpsO	SPRI_4591	SPRI_2166	Integration host factor; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.	30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.	0.700
SPRI_4591	rpsT	SPRI_4591	SPRI_4960	Integration host factor; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.	30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.	0.751
SPRI_4591	tig	SPRI_4591	SPRI_4898	Integration host factor; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.	Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.534
atpC	SPRI_4591	SPRI_2516	SPRI_4591	F0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Integration host factor; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.	0.564
atpC	rplL	SPRI_2516	SPRI_3202	F0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane.	50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.	0.837
atpC	rpsO	SPRI_2516	SPRI_2166	F0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane.	30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.	0.545

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