Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRI_4635Transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (197 aa)    
Predicted Functional Partners:
clpS
ATP-dependent Clp protease adapter protein clpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.
 
  
 0.931
SPRI_6177
MerR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
    0.810
SPRI_4633
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
       0.768
SPRI_4637
Peptidase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.699
SPRI_4632
Amidase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.669
SPRI_4639
Cysteine synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.640
SPRI_4070
Histidine kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
    0.639
SPRI_4638
Molybdenum cofactor biosynthesis protein MoaD; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.608
SPRI_3650
D-alanine glycine permease; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.528
SPRI_2693
Helicase UvrD; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the helicase family. UvrD subfamily.
  
     0.490
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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