STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_4640MBL fold metallo-hydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (250 aa)    
Predicted Functional Partners:
SPRI_1388
Endonuclease; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
   0.869
SPRI_4638
Molybdenum cofactor biosynthesis protein MoaD; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.731
SPRI_4639
Cysteine synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.731
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
  
  
 0.665
SPRI_4637
Peptidase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
    0.634
SPRI_3536
Crp/Fnr family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   
 0.527
SPRI_5351
Ubiquinol-cytochrome c reductase cytochrome b subunit; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.469
SPRI_5103
DUF3052 domain containing protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.432
argR
Arginine repressor; Regulates arginine biosynthesis genes.
  
     0.418
SPRI_4633
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
     
 0.415
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.