Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_4648HNH endonuclease; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (223 aa)    
Predicted Functional Partners:
SPRI_4647
Endonuclease; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
    
0.896
SPRI_4650
Peroxiredoxin; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.668
SPRI_6031
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.642
SPRI_4651
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.633
SPRI_4652
Chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter; Belongs to the GroES chaperonin family.
       0.590
SPRI_3966
Asparagine synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.558
SPRI_0582
PE-PGRS family protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.550
SPRI_2336
Transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.546
SPRI_6030
DUF4365 domain-containing protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.521
SPRI_4649
MFS transporter; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.516
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.