Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
SPRI_4654Penicillin-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (878 aa)    
Predicted Functional Partners:
SPRI_5427
Cell division protein DivIVA; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 
 0.788
mltG-2
Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
 
   
 0.686
SPRI_5419
Cell division protein FtsW; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the SEDS family.
  
  
 0.678
mltG
Membrane protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
 
   
 0.678
SPRI_4912
Rod shape-determining protein RodA; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the SEDS family.
 
 
 
 0.650
SPRI_3960
Peptidase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
   
 0.620
SPRI_2065
Peptidase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
   
 0.619
SPRI_0974
Peptidase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
   
 0.618
SPRI_2112
Kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   
 0.612
nusG
Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination.
 
   
 0.611
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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