STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_4723Histidine kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (610 aa)    
Predicted Functional Partners:
SPRI_2155
Two-component system sensor kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.997
SPRI_2359
Integral membrane phosphodiesterase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
0.989
SPRI_4097
Diguanylate cyclase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.859
SPRI_2944
Diguanylate cyclase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
0.827
SPRI_5565
Integral membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 0.719
SPRI_2654
Metal-dependent phosphohydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.696
SPRI_2248
DNA-directed RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.650
SPRI_0757
Diguanylate phosphodiesterase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 
0.647
SPRI_2154
Histidine kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.632
SPRI_1133
Histidine kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.551
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.