close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_4768Phosphatase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (262 aa)    
Predicted Functional Partners:
SPRI_4767
TetR-family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.745
SPRI_5239
DNA primase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.741
SPRI_4462
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.702
SPRI_4766
acetyl-CoA carboxylase subunit beta; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.693
SPRI_4764
hydroxymethylglutaryl-CoA lyase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.690
SPRI_2664
Fructose-1,6-bisphosphatase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.685
SPRI_2524
ATP synthase I; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.683
SPRI_3514
Anti-sigma regulatory factor; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.673
SPRI_6886
GAF domain protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.662
SPRI_5375
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.646
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: low (24%) [HD]