Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_4886DNA glycosylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the FPG family. (271 aa)    
Predicted Functional Partners:
SPRI_2144
DNA glycosylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the FPG family.
  
  
 
0.926
SPRI_4885
Ribose 5-phosphate isomerase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.800
SPRI_1532
ATP-dependent helicase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.588
SPRI_2143
DEAD/DEAH box helicase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.588
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
  
  
 0.564
uvrC
UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
  
  
 0.554
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.534
SPRI_4883
Biotin biosynthesis protein BioY; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.530
SPRI_4888
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.530
SPRI_4884
Gamma-aminobutyrate permease; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.402
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.