Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SPRI_4906Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (116 aa)    
Predicted Functional Partners:
SPRI_4905
Dihydrofolate synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.901
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
     
 0.814
SPRI_4910
Rod shape-determining protein MreD; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.782
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
 0.775
SPRI_2061
Phosphodiesterase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.741
SPRI_4911
Penicillin-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.704
SPRI_4903
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.695
SPRI_4909
Rod shape-determining protein MreC; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.693
SPRI_4912
Rod shape-determining protein RodA; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the SEDS family.
 
     0.676
SPRI_5879
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.663
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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