Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
ispD-22-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (517 aa)    
Predicted Functional Partners:
SPRI_4928
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.950
SPRI_6100
Ribulose-phosphate 3-epimerase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family.
  
 
 0.931
ispF
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
  
 0.908
SPRI_4929
Glycosyl transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 
 0.834
SPRI_0797
6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
  
 0.829
SPRI_2871
Carbohydrate kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
  0.819
SPRI_4885
Ribose 5-phosphate isomerase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
    
 0.819
SPRI_0186
PII peptide synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.802
SPRI_7167
PII peptide synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.802
SPRI_3782
6-phosphogluconate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
  0.800
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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