Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRI_4953Fatty acid-binding protein DegV; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (281 aa)    
Predicted Functional Partners:
SPRI_2292
Dihydroxyacetone kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.988
SPRI_4952
Secreted protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.716
leuS
leucyl-tRNA synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family.
     
 0.676
SPRI_4954
DNA-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.588
SPRI_4957
N-hydroxyarylamine O-acetyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the arylamine N-acetyltransferase family.
 
     0.584
SPRI_4955
Integral membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.530
rex
REX family transcriptional regulator; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
  
   
 0.520
SPRI_2392
TesB-like acyl-CoA thioesterase 3; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
    0.448
disA
Dna integrity scanning protein disa; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
  
    0.428
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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