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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_4963Protein phosphatase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (700 aa)    
Predicted Functional Partners:
SPRI_4964
Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
       0.866
SPRI_3515
Anti-sigma B factor antagonist; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family.
 
   0.846
SPRI_6891
Metal ABC transporter substrate-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family.
 
   0.792
SPRI_0646
Integral membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.765
SPRI_4488
Metal ABC transporter substrate-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family.
 
   0.764
SPRI_0527
Stage II sporulation protein E; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.763
SPRI_4962
AMP-dependent synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.739
SPRI_4049
Magnesium or manganese-dependent protein phosphatase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.737
SPRI_4888
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.712
SPRI_0826
Regulatory protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.709
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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