STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_4988Peptidase M4; Extracellular zinc metalloprotease. (351 aa)    
Predicted Functional Partners:
SPRI_4987
Metalloprotease; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.797
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
       0.722
SPRI_4990
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.657
SPRI_1817
Cellulose binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
  
 0.484
SPRI_3917
Amidohydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.423
SPRI_3253
Leupeptin-inactivating enzyme 1; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.404
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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