Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRI_5038Sirohydrochlorin cobaltochelatase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (250 aa)    
Predicted Functional Partners:
SPRI_6011
Uroporphyrinogen III methylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.
 
 0.993
SPRI_5039
Deoxyguanosinetriphosphate triphosphohydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the dGTPase family. Type 2 subfamily.
       0.806
cbiD
cobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
   
 0.761
SPRI_5667
Precorrin methylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   
 0.760
SPRI_3353
uroporphyrin-III C-methyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.744
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
     0.714
SPRI_6009
Methyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   
 0.712
SPRI_1662
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
 
  
 0.689
SPRI_1660
Nitrite/sulfate reductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.675
SPRI_5036
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.648
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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