Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_5042Ankyrin; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (327 aa)    
Predicted Functional Partners:
SPRI_5043
Ankyrin; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
      0.959
SPRI_5044
DNA-directed RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
       0.706
nusG
Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination.
   
    0.590
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
  
    0.544
SPRI_0491
Phosphodiesterase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.497
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
  
 
 0.483
SPRI_3421
Diguanylate cyclase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
  
 0.453
SPRI_3422
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.452
folE
GTP cyclohydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.435
folE-2
GTP cyclohydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.435
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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