node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KHO30716.1 | SecN | NX84_00595 | NX84_12025 | Preprotein translocase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit YajC; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.910 |
KHO30716.1 | ftsY | NX84_00595 | NX84_08975 | Preprotein translocase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.927 |
KHO30716.1 | secA | NX84_00595 | NX84_07535 | Preprotein translocase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.921 |
KHO30716.1 | secA1 | NX84_00595 | NX84_04575 | Preprotein translocase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.931 |
KHO30716.1 | secD | NX84_00595 | NX84_12030 | Preprotein translocase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.779 |
KHO30716.1 | secE | NX84_00595 | NX84_02970 | Preprotein translocase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.952 |
KHO30716.1 | secG | NX84_00595 | NX84_07000 | Preprotein translocase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.962 |
KHO30716.1 | secY | NX84_00595 | NX84_03285 | Preprotein translocase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.970 |
KHO30716.1 | srp | NX84_00595 | NX84_08930 | Preprotein translocase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.932 |
KHO30716.1 | yidC | NX84_00595 | NX84_01255 | Preprotein translocase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit YidC; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.908 |
SecN | KHO30716.1 | NX84_12025 | NX84_00595 | Preprotein translocase subunit YajC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.910 |
SecN | ftsY | NX84_12025 | NX84_08975 | Preprotein translocase subunit YajC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.959 |
SecN | secA | NX84_12025 | NX84_07535 | Preprotein translocase subunit YajC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.982 |
SecN | secA1 | NX84_12025 | NX84_04575 | Preprotein translocase subunit YajC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.982 |
SecN | secD | NX84_12025 | NX84_12030 | Preprotein translocase subunit YajC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.966 |
SecN | secE | NX84_12025 | NX84_02970 | Preprotein translocase subunit YajC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.973 |
SecN | secG | NX84_12025 | NX84_07000 | Preprotein translocase subunit YajC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.973 |
SecN | secY | NX84_12025 | NX84_03285 | Preprotein translocase subunit YajC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.963 |
SecN | srp | NX84_12025 | NX84_08930 | Preprotein translocase subunit YajC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.976 |
SecN | yidC | NX84_12025 | NX84_01255 | Preprotein translocase subunit YajC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit YidC; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.930 |