STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lipA_1Radical SAM protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (357 aa)    
Predicted Functional Partners:
lipB
Lipoate--protein ligase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
 
 0.999
gcvH
Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.964
lplA
Lipoate--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.931
aceF
Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.837
KHO29180.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.749
gcvP
Glycine dehydrogenase; Acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family.
  
  
 0.717
gcvT_2
Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine.
 
   
 0.691
maf
Septum formation inhibitor Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
   
  
 0.585
folE
GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.575
lpdA
Flavoprotein disulfide reductase; Catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone; does not have lipoamide dehydrogenase activity; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.573
Your Current Organism:
Corynebacterium minutissimum
NCBI taxonomy Id: 38301
Other names: ATCC 23348, C. minutissimum, CCUG 541, CIP 100652, DSM 20651, IFO 15361, JCM 9387, NBRC 15361, NCTC 10288
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