STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDM04803.1Aspartate aminotransferase. (381 aa)    
Predicted Functional Partners:
SDM04832.1
Histidinol-phosphate aminotransferase.
       0.773
SDL84030.1
Glycine dehydrogenase; Belongs to the GcvP family.
   
 
 0.701
SDL96342.1
Alanine-synthesizing transaminase.
  
 0.577
gcvT
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
   
 
 0.574
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.563
ilvA
L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 0.555
SDL90493.1
Phosphoserine phosphatase.
   
  0.528
SDL75597.1
L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
    
  0.517
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
     
 0.517
SDL68075.1
D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.509
Your Current Organism:
Corynebacterium mycetoides
NCBI taxonomy Id: 38302
Other names: ATCC 43995, C. mycetoides, CCUG 27538, CIP 55.51, DSM 20632, IFO 15289, JCM 9388, NBRC 15289, NCTC 9864
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