node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDL73193.1 | SDL75909.1 | SAMN04488535_0585 | SAMN04488535_0683 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein translocase subunit yajC. | 0.962 |
SDL73193.1 | SDL99029.1 | SAMN04488535_0585 | SAMN04488535_1486 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | YidC/Oxa1 family membrane protein insertase. | 0.979 |
SDL73193.1 | SDM02485.1 | SAMN04488535_0585 | SAMN04488535_1612 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | YidC/Oxa1 family membrane protein insertase. | 0.979 |
SDL73193.1 | ffh | SAMN04488535_0585 | SAMN04488535_0840 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.965 |
SDL73193.1 | ftsY | SAMN04488535_0585 | SAMN04488535_0843 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.983 |
SDL73193.1 | secA | SAMN04488535_0585 | SAMN04488535_0501 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.993 |
SDL73193.1 | secA-2 | SAMN04488535_0585 | SAMN04488535_2083 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.993 |
SDL73193.1 | secD | SAMN04488535_0585 | SAMN04488535_0682 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.967 |
SDL73193.1 | secE | SAMN04488535_0585 | SAMN04488535_1872 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.999 |
SDL73193.1 | secY | SAMN04488535_0585 | SAMN04488535_1930 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.999 |
SDL75909.1 | SDL73193.1 | SAMN04488535_0683 | SAMN04488535_0585 | Protein translocase subunit yajC. | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.962 |
SDL75909.1 | SDL99029.1 | SAMN04488535_0683 | SAMN04488535_1486 | Protein translocase subunit yajC. | YidC/Oxa1 family membrane protein insertase. | 0.900 |
SDL75909.1 | SDM02485.1 | SAMN04488535_0683 | SAMN04488535_1612 | Protein translocase subunit yajC. | YidC/Oxa1 family membrane protein insertase. | 0.921 |
SDL75909.1 | ffh | SAMN04488535_0683 | SAMN04488535_0840 | Protein translocase subunit yajC. | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.960 |
SDL75909.1 | ftsY | SAMN04488535_0683 | SAMN04488535_0843 | Protein translocase subunit yajC. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.955 |
SDL75909.1 | secA | SAMN04488535_0683 | SAMN04488535_0501 | Protein translocase subunit yajC. | Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.967 |
SDL75909.1 | secA-2 | SAMN04488535_0683 | SAMN04488535_2083 | Protein translocase subunit yajC. | Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.962 |
SDL75909.1 | secD | SAMN04488535_0683 | SAMN04488535_0682 | Protein translocase subunit yajC. | Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.954 |
SDL75909.1 | secE | SAMN04488535_0683 | SAMN04488535_1872 | Protein translocase subunit yajC. | Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.967 |
SDL75909.1 | secY | SAMN04488535_0683 | SAMN04488535_1930 | Protein translocase subunit yajC. | Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.961 |