Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Rcas_0002KEGG: rrs:RoseRS_0065 secreted hydrolase-like protein. (387 aa)    
Predicted Functional Partners:
Rcas_1858
PFAM: protein of unknown function DUF214; KEGG: rrs:RoseRS_2585 protein of unknown function DUF214.
  
 0.984
Rcas_0003
PFAM: thioesterase superfamily protein; KEGG: rrs:RoseRS_0066 thioesterase superfamily protein.
       0.645
Rcas_3240
PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: rrs:RoseRS_1877 AAA ATPase, central domain protein.
  
    0.560
Rcas_1748
SMART: AAA ATPase; KEGG: rrs:RoseRS_2121 AAA ATPase.
  
    0.554
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
       0.512
Rcas_2742
AAA ATPase; KEGG: rrs:RoseRS_2674 AAA ATPase.
  
    0.503
Rcas_3044
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rrs:RoseRS_2431 ABC transporter related.
 
   
 0.502
Rcas_3955
Putative signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: rrs:RoseRS_1117 putative signal transduction histidine kinase.
  
     0.417
Rcas_1752
PFAM: Squalene/phytoene synthase; KEGG: rrs:RoseRS_2117 squalene/phytoene synthase.
  
  
 0.402
Your Current Organism:
Roseiflexus castenholzii
NCBI taxonomy Id: 383372
Other names: R. castenholzii DSM 13941, Roseiflexus castenholzii DSM 13941, Roseiflexus castenholzii HLO8, Roseiflexus castenholzii str. DSM 13941, Roseiflexus castenholzii strain DSM 13941
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