Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Rcas_0959Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: rrs:RoseRS_3486 integral membrane sensor signal transduction histidine kinase. (471 aa)    
Predicted Functional Partners:
Rcas_0960
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rrs:RoseRS_3485 two component transcriptional regulator, winged helix family.
   0.957
Rcas_4445
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rrs:RoseRS_0761 two component transcriptional regulator, winged helix family.
 
   0.934
Rcas_1113
KEGG: rrs:RoseRS_3771 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
0.916
Rcas_3134
PFAM: response regulator receiver; KEGG: rrs:RoseRS_2347 response regulator receiver protein.
 
   0.878
Rcas_4344
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rrs:RoseRS_0195 two component transcriptional regulator, winged helix family.
 
   0.850
Rcas_0867
PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: rrs:RoseRS_4489 periplasmic binding protein/LacI transcriptional regulator.
 
  
 
 0.848
Rcas_3883
KEGG: rrs:RoseRS_0856 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
 
 0.846
Rcas_2286
PFAM: response regulator receiver; KEGG: rrs:RoseRS_1527 response regulator receiver protein.
 
 0.843
Rcas_0674
PFAM: response regulator receiver; KEGG: rrs:RoseRS_0161 response regulator receiver protein.
  
   0.824
Rcas_1504
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rrs:RoseRS_3737 two component transcriptional regulator, winged helix family.
   0.824
Your Current Organism:
Roseiflexus castenholzii
NCBI taxonomy Id: 383372
Other names: R. castenholzii DSM 13941, Roseiflexus castenholzii DSM 13941, Roseiflexus castenholzii HLO8, Roseiflexus castenholzii str. DSM 13941, Roseiflexus castenholzii strain DSM 13941
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