STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rcas_1010CRISPR-associated helicase Cas3; KEGG: afu:AF0071 ATP-dependent RNA helicase, putative; TIGRFAM: CRISPR-associated helicase Cas3; PFAM: DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases. (859 aa)    
Predicted Functional Partners:
Rcas_1012
TIGRFAM: CRISPR-associated autoregulator DevR family; PFAM: CRISPR-associated regulatory Csa2 family protein; KEGG: afu:AF0068 hypothetical protein.
  
 
 0.812
Rcas_1011
Hypothetical protein.
       0.802
Rcas_3305
CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
 
  
 0.788
Rcas_3302
KEGG: rrs:RoseRS_1869 hypothetical protein.
 
   
 0.787
Rcas_1009
KEGG: rrs:RoseRS_0652 regulatory protein, DeoR.
       0.785
cas1-3
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.764
Rcas_3300
TIGRFAM: CRISPR-associated protein Cas5 family; CRISPR-associated protein Cas5; KEGG: rrs:RoseRS_1867 CRISPR-associated protein Cas5 family.
  
 
 0.728
Rcas_1013
Hypothetical protein; KEGG: afu:AF0067 A. fulgidus predicted coding region AF0067.
       0.693
Rcas_3299
TIGRFAM: CRISPR-associated autoregulator DevR family; CRISPR-associated regulatory protein, DevR family; KEGG: rrs:RoseRS_1866 CRISPR-associated autoregulator, DevR family.
 
 
 0.692
cas1-2
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.613
Your Current Organism:
Roseiflexus castenholzii
NCBI taxonomy Id: 383372
Other names: R. castenholzii DSM 13941, Roseiflexus castenholzii DSM 13941, Roseiflexus castenholzii HLO8, Roseiflexus castenholzii str. DSM 13941, Roseiflexus castenholzii strain DSM 13941
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