STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rcas_1810PFAM: DNA methylase N-4/N-6 domain protein; KEGG: tel:tlr1878 DNA-methyltransferase; Belongs to the N(4)/N(6)-methyltransferase family. (329 aa)    
Predicted Functional Partners:
lexA
SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
    
 0.810
Rcas_1811
PFAM: aminotransferase class-III; KEGG: rrs:RoseRS_2608 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
       0.773
Rcas_1812
PFAM: metallophosphoesterase; KEGG: rrs:RoseRS_2607 metallophosphoesterase.
       0.773
Rcas_1171
PFAM: DNA methylase N-4/N-6 domain protein; KEGG: rrs:RoseRS_4284 DNA methylase N-4/N-6 domain protein; Belongs to the N(4)/N(6)-methyltransferase family.
  
     0.730
Rcas_2236
KEGG: hhe:HH0238 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase.
 
  
 0.642
Rcas_0884
KEGG: rrs:RoseRS_0233 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase.
 
  
 0.540
Rcas_4397
KEGG: rrs:RoseRS_2284 hypothetical protein.
 
   
 0.510
Rcas_1813
KEGG: rrs:RoseRS_2606 hypothetical protein.
       0.482
Rcas_3593
PFAM: DNA methylase N-4/N-6 domain protein; KEGG: rrs:RoseRS_0953 DNA methylase N-4/N-6 domain protein; Belongs to the N(4)/N(6)-methyltransferase family.
  
     0.474
Rcas_2134
PFAM: D12 class N6 adenine-specific DNA methyltransferase; KEGG: rrs:RoseRS_3043 D12 class N6 adenine-specific DNA methyltransferase.
 
  
 0.469
Your Current Organism:
Roseiflexus castenholzii
NCBI taxonomy Id: 383372
Other names: R. castenholzii DSM 13941, Roseiflexus castenholzii DSM 13941, Roseiflexus castenholzii HLO8, Roseiflexus castenholzii str. DSM 13941, Roseiflexus castenholzii strain DSM 13941
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