node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rcas_4199 | purC | Rcas_4199 | Rcas_1843 | KEGG: rrs:RoseRS_0043 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | PFAM: SAICAR synthetase; KEGG: rrs:RoseRS_2552 phosphoribosylaminoimidazolesuccinocarboxamide synthase. | 0.995 |
Rcas_4199 | purD | Rcas_4199 | Rcas_3175 | KEGG: rrs:RoseRS_0043 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | KEGG: rrs:RoseRS_2692 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; oxidoreductase domain protein; protein of unknown function DUF201; Belongs to the GARS family. | 0.877 |
Rcas_4199 | purE | Rcas_4199 | Rcas_2524 | KEGG: rrs:RoseRS_0043 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.948 |
Rcas_4199 | purF | Rcas_4199 | Rcas_1511 | KEGG: rrs:RoseRS_0043 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.957 |
Rcas_4199 | purH | Rcas_4199 | Rcas_4336 | KEGG: rrs:RoseRS_0043 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | KEGG: rrs:RoseRS_0206 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. | 0.995 |
Rcas_4199 | purK | Rcas_4199 | Rcas_2525 | KEGG: rrs:RoseRS_0043 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.948 |
Rcas_4199 | purL | Rcas_4199 | Rcas_1795 | KEGG: rrs:RoseRS_0043 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.999 |
Rcas_4199 | purM | Rcas_4199 | Rcas_1844 | KEGG: rrs:RoseRS_0043 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | KEGG: rrs:RoseRS_2554 phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein. | 0.944 |
Rcas_4199 | purN | Rcas_4199 | Rcas_3176 | KEGG: rrs:RoseRS_0043 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.929 |
Rcas_4199 | purQ | Rcas_4199 | Rcas_3277 | KEGG: rrs:RoseRS_0043 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.931 |
purC | Rcas_4199 | Rcas_1843 | Rcas_4199 | PFAM: SAICAR synthetase; KEGG: rrs:RoseRS_2552 phosphoribosylaminoimidazolesuccinocarboxamide synthase. | KEGG: rrs:RoseRS_0043 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.995 |
purC | purD | Rcas_1843 | Rcas_3175 | PFAM: SAICAR synthetase; KEGG: rrs:RoseRS_2552 phosphoribosylaminoimidazolesuccinocarboxamide synthase. | KEGG: rrs:RoseRS_2692 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; oxidoreductase domain protein; protein of unknown function DUF201; Belongs to the GARS family. | 0.964 |
purC | purE | Rcas_1843 | Rcas_2524 | PFAM: SAICAR synthetase; KEGG: rrs:RoseRS_2552 phosphoribosylaminoimidazolesuccinocarboxamide synthase. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.999 |
purC | purF | Rcas_1843 | Rcas_1511 | PFAM: SAICAR synthetase; KEGG: rrs:RoseRS_2552 phosphoribosylaminoimidazolesuccinocarboxamide synthase. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.987 |
purC | purH | Rcas_1843 | Rcas_4336 | PFAM: SAICAR synthetase; KEGG: rrs:RoseRS_2552 phosphoribosylaminoimidazolesuccinocarboxamide synthase. | KEGG: rrs:RoseRS_0206 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. | 0.985 |
purC | purK | Rcas_1843 | Rcas_2525 | PFAM: SAICAR synthetase; KEGG: rrs:RoseRS_2552 phosphoribosylaminoimidazolesuccinocarboxamide synthase. | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.993 |
purC | purL | Rcas_1843 | Rcas_1795 | PFAM: SAICAR synthetase; KEGG: rrs:RoseRS_2552 phosphoribosylaminoimidazolesuccinocarboxamide synthase. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.999 |
purC | purM | Rcas_1843 | Rcas_1844 | PFAM: SAICAR synthetase; KEGG: rrs:RoseRS_2552 phosphoribosylaminoimidazolesuccinocarboxamide synthase. | KEGG: rrs:RoseRS_2554 phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein. | 0.985 |
purC | purN | Rcas_1843 | Rcas_3176 | PFAM: SAICAR synthetase; KEGG: rrs:RoseRS_2552 phosphoribosylaminoimidazolesuccinocarboxamide synthase. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.986 |
purC | purQ | Rcas_1843 | Rcas_3277 | PFAM: SAICAR synthetase; KEGG: rrs:RoseRS_2552 phosphoribosylaminoimidazolesuccinocarboxamide synthase. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.972 |