Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Rcas_1963PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: rrs:RoseRS_2925 amine oxidase. (446 aa)    
Predicted Functional Partners:
Rcas_1864
PFAM: amine oxidase; KEGG: rrs:RoseRS_2594 amine oxidase.
  
  
 
0.925
Rcas_0272
PFAM: aldehyde dehydrogenase; KEGG: rrs:RoseRS_0265 aldehyde dehydrogenase (NAD(+)); Belongs to the aldehyde dehydrogenase family.
   
 0.909
Rcas_4434
PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: rrs:RoseRS_0752 alcohol dehydrogenase GroES domain protein.
    
  0.903
Rcas_1078
PFAM: histone deacetylase superfamily; KEGG: rrs:RoseRS_3805 histone deacetylase superfamily.
   
 0.598
Rcas_2918
PFAM: histone deacetylase superfamily; KEGG: rrs:RoseRS_3190 histone deacetylase superfamily.
   
 0.598
Rcas_3448
PFAM: histone deacetylase superfamily; KEGG: rrs:RoseRS_1584 histone deacetylase superfamily.
   
 0.598
Rcas_1609
PFAM: SNF2-related protein; helicase domain protein; type III restriction protein res subunit; SMART: DEAD-like helicases; KEGG: rrs:RoseRS_0240 helicase domain protein.
    
 0.541
Rcas_3328
KEGG: rrs:RoseRS_3980 non-specific serine/threonine protein kinase; PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicases.
    
 0.541
Rcas_0749
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
  
 0.519
ddl
D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
      
 0.516
Your Current Organism:
Roseiflexus castenholzii
NCBI taxonomy Id: 383372
Other names: R. castenholzii DSM 13941, Roseiflexus castenholzii DSM 13941, Roseiflexus castenholzii HLO8, Roseiflexus castenholzii str. DSM 13941, Roseiflexus castenholzii strain DSM 13941
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