STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rcas_1983Hypothetical protein; KEGG: cya:CYA_0883 CRISPR-associated protein Cas6. (287 aa)    
Predicted Functional Partners:
cas2
CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.828
Rcas_1981
TIGRFAM: CRISPR-associated RAMP protein, Csm5 family; KEGG: ptr:743860 hypothetical protein LOC743860.
 
   
 0.795
Rcas_1980
TIGRFAM: CRISPR-associated RAMP protein, Csm4 family; KEGG: chy:CHY_2141 CRISPR-associated RAMP protein, Csm4 family.
 
   
 0.784
Rcas_1977
TIGRFAM: CRISPR-associated protein, Csm1 family; KEGG: csc:Csac_0075 CRISPR-associated protein, Csm1 family.
 
  
 0.780
cas1
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.755
Rcas_0465
PFAM: O-antigen polymerase; KEGG: rrs:RoseRS_4235 O-antigen polymerase.
  
     0.686
Rcas_1979
TIGRFAM: CRISPR-associated RAMP protein, Csm3 family; PFAM: protein of unknown function DUF324; KEGG: tpt:Tpet_1095 CRISPR-associated RAMP protein, Csm3 family.
 
   
 0.676
Rcas_1978
TIGRFAM: CRISPR-associated protein, Csm2 family; PFAM: protein of unknown function DUF310; KEGG: chy:CHY_2143 CRISPR-associated protein, Csm2 family.
 
   
 0.664
Rcas_3299
TIGRFAM: CRISPR-associated autoregulator DevR family; CRISPR-associated regulatory protein, DevR family; KEGG: rrs:RoseRS_1866 CRISPR-associated autoregulator, DevR family.
 
   
 0.652
Rcas_3305
CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
 
   
 0.608
Your Current Organism:
Roseiflexus castenholzii
NCBI taxonomy Id: 383372
Other names: R. castenholzii DSM 13941, Roseiflexus castenholzii DSM 13941, Roseiflexus castenholzii HLO8, Roseiflexus castenholzii str. DSM 13941, Roseiflexus castenholzii strain DSM 13941
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.