Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Rcas_1990PFAM: iron-containing alcohol dehydrogenase; KEGG: rrs:RoseRS_1719 iron-containing alcohol dehydrogenase. (390 aa)    
Predicted Functional Partners:
Rcas_4434
PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: rrs:RoseRS_0752 alcohol dehydrogenase GroES domain protein.
  
 
 0.809
Rcas_4052
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rrs:RoseRS_1213 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
  
  
 0.582
glgA
Glycogen/starch synthase, ADP-glucose type; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
   
    0.569
Rcas_2213
PFAM: Radical SAM domain protein; KEGG: rrs:RoseRS_2430 radical SAM domain protein.
  
  
 0.496
Rcas_3524
KEGG: rrs:RoseRS_2148 pyruvate-formate lyase-activating enzyme-like protein.
  
  
 0.496
Rcas_1989
Hypothetical protein.
       0.480
Rcas_1991
Membrane protein-like protein; KEGG: cya:CYA_1695 hypothetical protein.
       0.466
Rcas_1992
KEGG: rrs:RoseRS_0853 membrane protein-like protein.
       0.466
Rcas_0272
PFAM: aldehyde dehydrogenase; KEGG: rrs:RoseRS_0265 aldehyde dehydrogenase (NAD(+)); Belongs to the aldehyde dehydrogenase family.
 
 
 0.461
Rcas_1887
PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: rrs:RoseRS_2970 3-hydroxyacyl-CoA dehydrogenase, NAD-binding.
  
 
 0.447
Your Current Organism:
Roseiflexus castenholzii
NCBI taxonomy Id: 383372
Other names: R. castenholzii DSM 13941, Roseiflexus castenholzii DSM 13941, Roseiflexus castenholzii HLO8, Roseiflexus castenholzii str. DSM 13941, Roseiflexus castenholzii strain DSM 13941
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