Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Rcas_2010PFAM: DNA methylase N-4/N-6 domain protein; KEGG: rrs:RoseRS_0375 DNA methylase N-4/N-6 domain protein; Belongs to the N(4)/N(6)-methyltransferase family. (370 aa)    
Predicted Functional Partners:
Rcas_2009
PFAM: CBS domain containing protein; KEGG: rrs:RoseRS_1725 putative signal-transduction protein with CBS domains.
       0.678
lexA
SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
    
 0.590
Rcas_1171
PFAM: DNA methylase N-4/N-6 domain protein; KEGG: rrs:RoseRS_4284 DNA methylase N-4/N-6 domain protein; Belongs to the N(4)/N(6)-methyltransferase family.
  
     0.589
Rcas_2008
PFAM: transferase hexapeptide repeat containing protein; KEGG: rrs:RoseRS_1724 transferase hexapeptide repeat containing protein.
       0.569
Rcas_2006
PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: rrs:RoseRS_1722 Glu/Leu/Phe/Val dehydrogenase, C terminal; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
    0.492
Rcas_2007
PFAM: protein of unknown function UPF0102; KEGG: rrs:RoseRS_1723 protein of unknown function UPF0102; Belongs to the UPF0102 family.
       0.484
Rcas_2236
KEGG: hhe:HH0238 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase.
  
 0.471
Rcas_0884
KEGG: rrs:RoseRS_0233 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase.
 
  
 0.457
Rcas_4038
PFAM: putative RNA methylase; KEGG: rrs:RoseRS_2251 hypothetical protein; Belongs to the N(4)/N(6)-methyltransferase family.
  
     0.427
Your Current Organism:
Roseiflexus castenholzii
NCBI taxonomy Id: 383372
Other names: R. castenholzii DSM 13941, Roseiflexus castenholzii DSM 13941, Roseiflexus castenholzii HLO8, Roseiflexus castenholzii str. DSM 13941, Roseiflexus castenholzii strain DSM 13941
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