node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rcas_1811 | Rcas_2031 | Rcas_1811 | Rcas_2031 | PFAM: aminotransferase class-III; KEGG: rrs:RoseRS_2608 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.468 |
Rcas_1811 | Rcas_2032 | Rcas_1811 | Rcas_2032 | PFAM: aminotransferase class-III; KEGG: rrs:RoseRS_2608 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: rrs:RoseRS_1752 porphobilinogen synthase; Belongs to the ALAD family. | 0.987 |
Rcas_1811 | hemA | Rcas_1811 | Rcas_2026 | PFAM: aminotransferase class-III; KEGG: rrs:RoseRS_2608 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.983 |
Rcas_1811 | hemC | Rcas_1811 | Rcas_2030 | PFAM: aminotransferase class-III; KEGG: rrs:RoseRS_2608 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.858 |
Rcas_2031 | Rcas_1811 | Rcas_2031 | Rcas_1811 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | PFAM: aminotransferase class-III; KEGG: rrs:RoseRS_2608 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.468 |
Rcas_2031 | Rcas_2032 | Rcas_2031 | Rcas_2032 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: rrs:RoseRS_1752 porphobilinogen synthase; Belongs to the ALAD family. | 0.967 |
Rcas_2031 | Rcas_2628 | Rcas_2031 | Rcas_2628 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | PFAM: aminotransferase class-III; KEGG: dsy:DSY2219 hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.488 |
Rcas_2031 | Rcas_3843 | Rcas_2031 | Rcas_3843 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | PFAM: aminotransferase class-III; KEGG: pai:PAE0594 glutamate-1-semialdehyde aminotransferase (hemL); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.542 |
Rcas_2031 | hemA | Rcas_2031 | Rcas_2026 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.958 |
Rcas_2031 | hemC | Rcas_2031 | Rcas_2030 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.999 |
Rcas_2031 | hemE | Rcas_2031 | Rcas_2028 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.983 |
Rcas_2031 | hemH-2 | Rcas_2031 | Rcas_2029 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.868 |
Rcas_2031 | hemL | Rcas_2031 | Rcas_2033 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: rrs:RoseRS_1753 glutamate-1-semialdehyde-2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.664 |
Rcas_2032 | Rcas_1811 | Rcas_2032 | Rcas_1811 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: rrs:RoseRS_1752 porphobilinogen synthase; Belongs to the ALAD family. | PFAM: aminotransferase class-III; KEGG: rrs:RoseRS_2608 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.987 |
Rcas_2032 | Rcas_2031 | Rcas_2032 | Rcas_2031 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: rrs:RoseRS_1752 porphobilinogen synthase; Belongs to the ALAD family. | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.967 |
Rcas_2032 | Rcas_2628 | Rcas_2032 | Rcas_2628 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: rrs:RoseRS_1752 porphobilinogen synthase; Belongs to the ALAD family. | PFAM: aminotransferase class-III; KEGG: dsy:DSY2219 hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.988 |
Rcas_2032 | Rcas_3843 | Rcas_2032 | Rcas_3843 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: rrs:RoseRS_1752 porphobilinogen synthase; Belongs to the ALAD family. | PFAM: aminotransferase class-III; KEGG: pai:PAE0594 glutamate-1-semialdehyde aminotransferase (hemL); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.988 |
Rcas_2032 | hemA | Rcas_2032 | Rcas_2026 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: rrs:RoseRS_1752 porphobilinogen synthase; Belongs to the ALAD family. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.884 |
Rcas_2032 | hemC | Rcas_2032 | Rcas_2030 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: rrs:RoseRS_1752 porphobilinogen synthase; Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.997 |
Rcas_2032 | hemE | Rcas_2032 | Rcas_2028 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: rrs:RoseRS_1752 porphobilinogen synthase; Belongs to the ALAD family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.673 |