STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rcas_2073TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: rrs:RoseRS_1483 cation diffusion facilitator family transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (308 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
    0.829
Rcas_1788
KEGG: rrs:RoseRS_2073 cation efflux protein.
 
 
 0.537
Rcas_3322
PFAM: iron dependent repressor; FeoA family protein; KEGG: rrs:RoseRS_3986 FeoA family protein.
     
 0.448
Rcas_3669
PFAM: response regulator receiver; KEGG: rrs:RoseRS_4041 response regulator receiver protein.
  
    0.442
Rcas_2316
Transcriptional regulator, ArsR family; PFAM: low molecular weight phosphotyrosine protein phosphatase; regulatory protein ArsR; KEGG: rrs:RoseRS_1228 protein tyrosine phosphatase.
  
  
 0.430
Rcas_4261
PFAM: FeoA family protein; KEGG: rrs:RoseRS_0552 FeoA family protein.
     
 0.427
Rcas_2072
KEGG: rrs:RoseRS_1482 hypothetical protein.
       0.421
cmk
KEGG: rrs:RoseRS_0324 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region.
  
    0.407
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
 
    0.406
Rcas_2783
PFAM: protein of unknown function DUF305; KEGG: rrs:RoseRS_4123 protein of unknown function DUF305.
 
   
 0.405
Your Current Organism:
Roseiflexus castenholzii
NCBI taxonomy Id: 383372
Other names: R. castenholzii DSM 13941, Roseiflexus castenholzii DSM 13941, Roseiflexus castenholzii HLO8, Roseiflexus castenholzii str. DSM 13941, Roseiflexus castenholzii strain DSM 13941
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