| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rcas_0057 | Rcas_0748 | Rcas_0057 | Rcas_0748 | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rrs:RoseRS_3319 threonine dehydratase. | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rrs:RoseRS_4405 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | 0.916 |
| Rcas_0057 | Rcas_2139 | Rcas_0057 | Rcas_2139 | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rrs:RoseRS_3319 threonine dehydratase. | TIGRFAM: serine O-acetyltransferase; KEGG: rrs:RoseRS_3035 serine O-acetyltransferase. | 0.831 |
| Rcas_0057 | Rcas_3211 | Rcas_0057 | Rcas_3211 | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rrs:RoseRS_3319 threonine dehydratase. | TIGRFAM: phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: rrs:RoseRS_3902 phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein. | 0.909 |
| Rcas_0057 | glyA | Rcas_0057 | Rcas_1155 | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rrs:RoseRS_3319 threonine dehydratase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.932 |
| Rcas_0315 | Rcas_1559 | Rcas_0315 | Rcas_1559 | TIGRFAM: cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rrs:RoseRS_0720 cysteine synthase. | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: rrs:RoseRS_1971 homoserine dehydrogenase. | 0.408 |
| Rcas_0315 | Rcas_2086 | Rcas_0315 | Rcas_2086 | TIGRFAM: cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rrs:RoseRS_0720 cysteine synthase. | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: rrs:RoseRS_2987 homoserine dehydrogenase. | 0.402 |
| Rcas_0315 | Rcas_2139 | Rcas_0315 | Rcas_2139 | TIGRFAM: cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rrs:RoseRS_0720 cysteine synthase. | TIGRFAM: serine O-acetyltransferase; KEGG: rrs:RoseRS_3035 serine O-acetyltransferase. | 0.990 |
| Rcas_0315 | cysS | Rcas_0315 | Rcas_2138 | TIGRFAM: cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rrs:RoseRS_0720 cysteine synthase. | KEGG: rrs:RoseRS_3036 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.905 |
| Rcas_0315 | cysS-2 | Rcas_0315 | Rcas_4315 | TIGRFAM: cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rrs:RoseRS_0720 cysteine synthase. | TIGRFAM: cysteinyl-tRNA synthetase; PFAM: tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; KEGG: rrs:RoseRS_3331 cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.890 |
| Rcas_0748 | Rcas_0057 | Rcas_0748 | Rcas_0057 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rrs:RoseRS_4405 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rrs:RoseRS_3319 threonine dehydratase. | 0.916 |
| Rcas_0748 | Rcas_2139 | Rcas_0748 | Rcas_2139 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rrs:RoseRS_4405 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | TIGRFAM: serine O-acetyltransferase; KEGG: rrs:RoseRS_3035 serine O-acetyltransferase. | 0.819 |
| Rcas_0748 | Rcas_3211 | Rcas_0748 | Rcas_3211 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rrs:RoseRS_4405 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | TIGRFAM: phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: rrs:RoseRS_3902 phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein. | 0.909 |
| Rcas_0748 | glyA | Rcas_0748 | Rcas_1155 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rrs:RoseRS_4405 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.914 |
| Rcas_1559 | Rcas_0315 | Rcas_1559 | Rcas_0315 | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: rrs:RoseRS_1971 homoserine dehydrogenase. | TIGRFAM: cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rrs:RoseRS_0720 cysteine synthase. | 0.408 |
| Rcas_1559 | Rcas_2086 | Rcas_1559 | Rcas_2086 | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: rrs:RoseRS_1971 homoserine dehydrogenase. | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: rrs:RoseRS_2987 homoserine dehydrogenase. | 0.916 |
| Rcas_1559 | Rcas_2139 | Rcas_1559 | Rcas_2139 | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: rrs:RoseRS_1971 homoserine dehydrogenase. | TIGRFAM: serine O-acetyltransferase; KEGG: rrs:RoseRS_3035 serine O-acetyltransferase. | 0.858 |
| Rcas_1559 | Rcas_3211 | Rcas_1559 | Rcas_3211 | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: rrs:RoseRS_1971 homoserine dehydrogenase. | TIGRFAM: phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: rrs:RoseRS_3902 phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein. | 0.923 |
| Rcas_2086 | Rcas_0315 | Rcas_2086 | Rcas_0315 | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: rrs:RoseRS_2987 homoserine dehydrogenase. | TIGRFAM: cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rrs:RoseRS_0720 cysteine synthase. | 0.402 |
| Rcas_2086 | Rcas_1559 | Rcas_2086 | Rcas_1559 | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: rrs:RoseRS_2987 homoserine dehydrogenase. | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: rrs:RoseRS_1971 homoserine dehydrogenase. | 0.916 |
| Rcas_2086 | Rcas_2139 | Rcas_2086 | Rcas_2139 | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: rrs:RoseRS_2987 homoserine dehydrogenase. | TIGRFAM: serine O-acetyltransferase; KEGG: rrs:RoseRS_3035 serine O-acetyltransferase. | 0.864 |