STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rcas_2456Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: rrs:RoseRS_2856 periplasmic binding protein/LacI transcriptional regulator. (352 aa)    
Predicted Functional Partners:
Rcas_2048
TIGRFAM: phosphocarrier, HPr family; phosphoenolpyruvate-protein phosphotransferase; dihydroxyacetone kinase, phosphotransfer subunit; PFAM: phosphocarrier HPr protein; PEP-utilizing protein; PTS system fructose subfamily IIA component; PEP-utilising protein mobile region; PEP-utilising protein domain protein; KEGG: rrs:RoseRS_1770 phosphoenolpyruvate-protein phosphotransferase; Belongs to the PEP-utilizing enzyme family.
   
 
 0.908
Rcas_1903
PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: rrs:RoseRS_2985 glutamate synthase (ferredoxin).
    
 
 0.886
Rcas_4115
TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: rrs:RoseRS_3303 phosphotransferase system, phosphocarrier protein HPr.
   
 
 0.737
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
    
   0.674
cysC
Sulfate adenylyltransferase; Catalyzes the synthesis of activated sulfate.
    
   0.674
Rcas_2458
PFAM: protein of unknown function DUF993; KEGG: rrs:RoseRS_2854 protein of unknown function DUF993.
 
   
 0.630
Rcas_2457
PFAM: oxidoreductase domain protein; KEGG: rrs:RoseRS_2855 oxidoreductase domain protein.
 
     0.621
Rcas_2459
PFAM: Xylose isomerase domain protein TIM barrel; KEGG: rrs:RoseRS_2853 xylose isomerase domain protein TIM barrel.
 
    0.617
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 
 0.614
pheT
KEGG: rrs:RoseRS_1038 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit.
   
   0.596
Your Current Organism:
Roseiflexus castenholzii
NCBI taxonomy Id: 383372
Other names: R. castenholzii DSM 13941, Roseiflexus castenholzii DSM 13941, Roseiflexus castenholzii HLO8, Roseiflexus castenholzii str. DSM 13941, Roseiflexus castenholzii strain DSM 13941
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