STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rcas_3206KEGG: rrs:RoseRS_3911 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)    
Predicted Functional Partners:
Rcas_1887
PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: rrs:RoseRS_2970 3-hydroxyacyl-CoA dehydrogenase, NAD-binding.
 
 0.999
Rcas_0982
TIGRFAM: putative hydroxymethylglutaryl-CoA synthase; PFAM: Hydroxymethylglutaryl-coenzyme A synthase domain; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; KEGG: rrs:RoseRS_0430 putative hydroxymethylglutaryl-CoA synthase.
  
 0.994
Rcas_0581
KEGG: rrs:RoseRS_3488 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 0.953
Rcas_1888
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: rrs:RoseRS_2971 acyl-CoA dehydrogenase domain protein.
  
 0.951
Rcas_1889
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: rrs:RoseRS_2972 acyl-CoA dehydrogenase domain protein.
  
 0.951
Rcas_4052
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rrs:RoseRS_1213 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
  
 
 0.936
Rcas_0984
PFAM: protein of unknown function DUF35; KEGG: rrs:RoseRS_0428 protein of unknown function DUF35.
  
 
 0.934
Rcas_2930
PFAM: AMP-dependent synthetase and ligase; Enoyl-CoA hydratase/isomerase; Alcohol dehydrogenase GroES domain protein; KEGG: rrs:RoseRS_3202 AMP-dependent synthetase and ligase.
  
 0.934
Rcas_3829
TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase; KEGG: rrs:RoseRS_1953 acetoacetyl-CoA synthase.
  
 
 0.927
Rcas_3934
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
  
 
 0.927
Your Current Organism:
Roseiflexus castenholzii
NCBI taxonomy Id: 383372
Other names: R. castenholzii DSM 13941, Roseiflexus castenholzii DSM 13941, Roseiflexus castenholzii HLO8, Roseiflexus castenholzii str. DSM 13941, Roseiflexus castenholzii strain DSM 13941
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.