Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Rcas_3208KEGG: rrs:RoseRS_3909 hypothetical protein. (689 aa)    
Predicted Functional Partners:
Rcas_3207
PFAM: WD-40 repeat protein; KEGG: rrs:RoseRS_3910 WD-40 repeat protein.
 
   
 0.905
Rcas_2348
KEGG: rrs:RoseRS_2010 hypothetical protein.
 
    0.773
Rcas_3206
KEGG: rrs:RoseRS_3911 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
       0.757
Rcas_1604
KEGG: ter:Tery_1841 peptidase C14, caspase catalytic subunit P20.
  
     0.644
Rcas_1992
KEGG: rrs:RoseRS_0853 membrane protein-like protein.
  
     0.637
Rcas_1150
PFAM: glycosyl transferase family 39; KEGG: rrs:RoseRS_0394 glycosyl transferase, family 39.
  
     0.620
Rcas_1439
KEGG: rrs:RoseRS_1037 hypothetical protein.
  
     0.610
Rcas_3209
KEGG: rrs:RoseRS_3908 hypothetical protein.
       0.554
Rcas_4061
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
   
   0.538
Rcas_1602
Putative signal transduction protein with Nacht domain; KEGG: rrs:RoseRS_2919 protein of unknown function DUF323.
  
     0.518
Your Current Organism:
Roseiflexus castenholzii
NCBI taxonomy Id: 383372
Other names: R. castenholzii DSM 13941, Roseiflexus castenholzii DSM 13941, Roseiflexus castenholzii HLO8, Roseiflexus castenholzii str. DSM 13941, Roseiflexus castenholzii strain DSM 13941
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