STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rcas_3523KEGG: rrs:RoseRS_2149 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24 S26A and S26B; Belongs to the peptidase S26 family. (243 aa)    
Predicted Functional Partners:
Rcas_3449
PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: rrs:RoseRS_1583 ATP dependent DNA ligase.
    
 0.831
Rcas_2690
PFAM: Lytic transglycosylase catalytic; Tetratricopeptide TPR_4; SMART: Tetratricopeptide domain protein; KEGG: rrs:RoseRS_2641 lytic transglycosylase, catalytic.
  
  
 0.792
minE
Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
   
    0.772
atpE
ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
    
 0.763
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
  
 
 0.758
rnhB
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
  
 0.758
Rcas_3522
PFAM: glycosyl transferase group 1; KEGG: rrs:RoseRS_2150 glycosyl transferase, group 1.
  
    0.741
Rcas_1427
PFAM: 60 kDa inner membrane insertion protein; KEGG: rrs:RoseRS_3965 60 kDa inner membrane insertion protein.
 
  
 0.644
Rcas_1903
PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: rrs:RoseRS_2985 glutamate synthase (ferredoxin).
     
 0.630
rpmF
TIGRFAM: ribosomal protein L32; PFAM: ribosomal L32p protein; KEGG: rrs:RoseRS_2613 ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
  
    0.587
Your Current Organism:
Roseiflexus castenholzii
NCBI taxonomy Id: 383372
Other names: R. castenholzii DSM 13941, Roseiflexus castenholzii DSM 13941, Roseiflexus castenholzii HLO8, Roseiflexus castenholzii str. DSM 13941, Roseiflexus castenholzii strain DSM 13941
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