STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rcas_3872KEGG: rrs:RoseRS_0545 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. (740 aa)    
Predicted Functional Partners:
Rcas_3871
KEGG: rrs:RoseRS_0544 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase.
 
 
0.997
Rcas_2999
KEGG: rrs:RoseRS_2025 LAO/AO transport system ATPase; TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; SMART: AAA ATPase.
  
 0.996
Rcas_3873
TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; KEGG: rrs:RoseRS_0546 LAO/AO transport system ATPase.
  
 0.993
Rcas_0152
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: rrs:RoseRS_0480 glyoxalase/bleomycin resistance protein/dioxygenase.
  
 0.983
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.945
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.937
Rcas_4052
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rrs:RoseRS_1213 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
    
 0.927
Rcas_0909
PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: rrs:RoseRS_4176 L-carnitine dehydratase/bile acid-inducible protein F; Belongs to the CoA-transferase III family.
    
 0.923
Rcas_0910
PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: rrs:RoseRS_4175 L-carnitine dehydratase/bile acid-inducible protein F; Belongs to the CoA-transferase III family.
    
 0.923
Rcas_0559
PFAM: AMP-dependent synthetase and ligase; KEGG: rrs:RoseRS_3859 AMP-dependent synthetase and ligase.
    
 0.912
Your Current Organism:
Roseiflexus castenholzii
NCBI taxonomy Id: 383372
Other names: R. castenholzii DSM 13941, Roseiflexus castenholzii DSM 13941, Roseiflexus castenholzii HLO8, Roseiflexus castenholzii str. DSM 13941, Roseiflexus castenholzii strain DSM 13941
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