Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Rcas_4100PFAM: ATP-binding region ATPase domain protein; KEGG: rrs:RoseRS_3290 putative anti-sigma regulatory factor, serine/threonine protein kinase. (154 aa)    
Predicted Functional Partners:
Rcas_4098
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: rrs:RoseRS_3288 anti-sigma-factor antagonist.
 
   0.922
Rcas_1195
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; ATP-binding region ATPase domain protein; KEGG: rrs:RoseRS_2161 anti-sigma-factor antagonist.
 
   0.861
Rcas_4210
PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: rrs:RoseRS_0032 stage II sporulation E family protein.
 
 
 0.847
Rcas_2849
Protein serine phosphatase with GAF(s) sensor(s); PFAM: GAF domain protein; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: rrs:RoseRS_2499 protein serine phosphatase with GAF(s) sensor(s).
 
 
 0.845
Rcas_1196
Protein serine phosphatase with GAF(s) sensor(s); PFAM: GAF domain protein; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: rrs:RoseRS_2162 protein serine phosphatase with GAF(s) sensor(s).
 
 
 0.838
Rcas_4099
KEGG: rrs:RoseRS_3289 putative anti-sigma regulatory factor, serine/threonine protein kinase.
 
    
0.834
Rcas_1117
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: rrs:RoseRS_3767 anti-sigma-factor antagonist.
 
   0.774
Rcas_1194
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: rrs:RoseRS_2160 anti-sigma-factor antagonist.
 
   0.711
Rcas_1114
PFAM: response regulator receiver; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: rrs:RoseRS_3770 response regulator receiver protein.
 
 
 0.630
Rcas_4067
KEGG: rrs:RoseRS_0604 putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 
 0.592
Your Current Organism:
Roseiflexus castenholzii
NCBI taxonomy Id: 383372
Other names: R. castenholzii DSM 13941, Roseiflexus castenholzii DSM 13941, Roseiflexus castenholzii HLO8, Roseiflexus castenholzii str. DSM 13941, Roseiflexus castenholzii strain DSM 13941
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