STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
M3AUM7_PSEFDUbiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (697 aa)    
Predicted Functional Partners:
M3B376_PSEFD
Autophagy-related protein 3.
  
 
 0.999
M3B8H5_PSEFD
Autophagy-related protein.
   
 0.999
N1Q9E0_PSEFD
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.
    
 0.999
M3AI21_PSEFD
Lipase_3 domain-containing protein.
   
 
 0.983
M2YRM7_PSEFD
Autophagy_act_C domain-containing protein.
   
 0.913
M3AS80_PSEFD
Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.
    
 0.883
M2YL00_PSEFD
Uncharacterized protein.
    
 0.880
M2ZCM6_PSEFD
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 0.843
M3AEW1_PSEFD
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.836
M2YKK3_PSEFD
UBA_e1_C domain-containing protein; Belongs to the ubiquitin-activating E1 family.
    
 0.829
Your Current Organism:
Pseudocercospora fijiensis
NCBI taxonomy Id: 383855
Other names: Cercospora fijiensis CIRAD86, Mycosphaerella fijiensis CIRAD86, P. fijiensis CIRAD86, Pseudocercospora fijiensis CIRAD86
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