Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_0089PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sai:Saci_1536 ABC transporter. (237 aa)    
Predicted Functional Partners:
Pisl_0090
Hypothetical protein; KEGG: sai:Saci_1535 conserved archaeal membrane protein.
       0.787
Pisl_2013
PFAM: ABC-2 type transporter; KEGG: pai:PAE0270 membrane protein.
 
  
 0.584
rpl14
LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
 
    0.528
Pisl_0088
PFAM: NUDIX hydrolase; KEGG: pai:PAE0252 diadenosine 5'5'''-P1,P4-tetraphosphate pyrophosphohydrolase (MutT/NUDIX family protein).
       0.489
Pisl_1969
PFAM: ABC-2 type transporter; KEGG: pai:PAE0316 ABC-2 type transport system, membrane protein.
  
  
 0.482
Pisl_0902
PFAM: ABC-2 type transporter; KEGG: pai:PAE3065 ABC-2 type transport system, membrane protein.
  
  
 0.479
Pisl_0087
KEGG: pai:PAE0167 hypothetical protein.
       0.459
fusA
Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...]
 
  
 0.441
ileS
Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
 
 
 0.436
Pisl_1019
KEGG: pai:PAE2297 valyl-tRNA synthetase.
 
 
 
 0.423
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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