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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Pisl_0109Amidophosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: pai:PAE0218 amidophosphoribosyltransferase (purF). (372 aa)    
Predicted Functional Partners:
Pisl_0106
Phosphoribosylamine--glycine ligase; KEGG: pai:PAE0216 phosphoribosylglycinamide synthetase (GARS) (purD); TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase.
 
 0.999
purQ
Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...]
 
 
 0.998
Pisl_0110
Phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: pai:PAE0221 phosphoribosylformylglycinamidine cyclo-ligase (AIRS) (purM).
 
  
 0.995
Pisl_0107
KEGG: pai:PAE0224 hypothetical protein.
  
  
 0.982
carB
TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: pai:PAE0947 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family.
 
 
 0.979
purC
PFAM: SAICAR synthetase; KEGG: pai:PAE0215 phosphoribosylaminoimidazole-succinocarboxamide synthase (purC).
 
 
 0.978
Pisl_1197
TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: pai:PAE0972 adenylosuccinate lyase.
  
 
 0.975
carA
TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase, small chain; KEGG: pai:PAE0946 carbamoyl-phosphate synthase small subunit; Belongs to the CarA family.
 
 
 0.970
Pisl_0102
Amidophosphoribosyltransferase; PFAM: glutamine amidotransferase, class-II; KEGG: pai:PAE0226 amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
  
 
0.966
purK
5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR); Belongs to the PurK/PurT family.
  
 
 0.962
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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