Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Pisl_0150PFAM: ATPase; KEGG: pai:PAE2540 hypothetical protein. (360 aa)    
Predicted Functional Partners:
Pisl_0994
KEGG: pai:PAE3468 hypothetical protein.
  
     0.614
Pisl_1907
TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase, IS605 OrfB; KEGG: pab:PAB2077 hypothetical protein.
  
     0.592
Pisl_0711
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: pai:PAE0656 hypothetical protein.
  
     0.567
Pisl_1067
TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase, IS605 OrfB; KEGG: sso:SSO1916 second ORF in transposon ISC1913.
  
     0.567
Pisl_0134
TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase, IS605 OrfB; KEGG: pab:PAB2077 hypothetical protein.
  
     0.565
Pisl_1191
KEGG: pai:PAE0967 hypothetical protein.
 
     0.501
Pisl_1431
PFAM: MscS Mechanosensitive ion channel; KEGG: pai:PAE1270 hypothetical protein.
 
     0.498
Pisl_1376
KEGG: sto:ST1143 hypothetical protein.
 
     0.484
Pisl_1257
KEGG: pai:PAE1069 hypothetical protein.
  
     0.482
Pisl_1536
PFAM: PilT protein domain protein; KEGG: tko:TK0374 predicted nucleic acid-binding protein, containing PIN domain.
 
     0.462
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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