Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_0168PFAM: DsrC family protein; KEGG: pai:PAE2566 siroheme-sulfite reductase gamma subunit homolog. (111 aa)    
Predicted Functional Partners:
Pisl_0170
KEGG: pai:PAE2571 sulfite reductase beta subunit; TIGRFAM: sulfite reductase, dissimilatory-type beta subunit; PFAM: nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region.
 
 
 
 0.948
Pisl_0171
KEGG: pai:PAE2572 sulfite reductase alpha subunit; TIGRFAM: sulfite reductase, dissimilatory-type alpha subunit; PFAM: nitrite and sulphite reductase 4Fe-4S region.
 
 
 
 0.947
Pisl_0174
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: pai:PAE1331 conserved iron-sulfur protein.
 
 
 
 0.706
Pisl_0172
PFAM: Nitrate reductase, gamma subunit; KEGG: pai:PAE2614 nitrate reductase gamma subunit.
 
   
 0.695
Pisl_0176
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: afu:AF0543 hypothetical protein.
 
 
 
 0.674
Pisl_0177
PFAM: Nitrate reductase, gamma subunit; KEGG: afu:AF0545 hypothetical protein.
 
   
 0.665
Pisl_0169
Hypothetical protein.
       0.657
Pisl_1962
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: pai:PAE1331 conserved iron-sulfur protein.
 
 
 
 0.651
Pisl_0167
PFAM: conserved hypothetical protein 698; KEGG: noc:Noc_1683 conserved hypothetical protein 698.
 
     0.632
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
     
 0.609
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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