Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_0174PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: pai:PAE1331 conserved iron-sulfur protein. (471 aa)    
Predicted Functional Partners:
Pisl_0170
KEGG: pai:PAE2571 sulfite reductase beta subunit; TIGRFAM: sulfite reductase, dissimilatory-type beta subunit; PFAM: nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region.
 
 
 0.976
Pisl_0171
KEGG: pai:PAE2572 sulfite reductase alpha subunit; TIGRFAM: sulfite reductase, dissimilatory-type alpha subunit; PFAM: nitrite and sulphite reductase 4Fe-4S region.
 
 
 0.975
Pisl_0172
PFAM: Nitrate reductase, gamma subunit; KEGG: pai:PAE2614 nitrate reductase gamma subunit.
 
 0.954
Pisl_0245
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: pai:PAE2371 NADH oxidase (nox).
  
 
 0.910
Pisl_0611
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; FAD dependent oxidoreductase; KEGG: pai:PAE2371 NADH oxidase (nox).
  
 
 0.910
Pisl_1761
Cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: pfu:PF1858 cysteine synthase.
    
 0.903
Pisl_0881
Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; KEGG: pai:PAE2420 cystathionine gamma-synthase.
    
 0.901
Pisl_0177
PFAM: Nitrate reductase, gamma subunit; KEGG: afu:AF0545 hypothetical protein.
 
 
 0.724
Pisl_0168
PFAM: DsrC family protein; KEGG: pai:PAE2566 siroheme-sulfite reductase gamma subunit homolog.
 
 
 
 0.706
Pisl_1342
PFAM: protein of unknown function DUF162; KEGG: pai:PAE1289 hypothetical protein.
  
 
 0.617
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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