Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Pisl_0182PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sto:ST1066 hypothetical protein. (255 aa)    
Predicted Functional Partners:
Pisl_1287
PFAM: ABC-3 protein; KEGG: pai:PAE1247 manganese transport permease protein.
  
 
 0.962
Pisl_0128
PFAM: periplasmic solute binding protein; KEGG: pai:PAE0564 putative zinc / manganese transport system substrate-binding protein.
  
  
 0.855
Pisl_0181
KEGG: sai:Saci_1065 hypothetical protein.
       0.850
Pisl_0184
SMART: regulatory protein, ArsR; KEGG: sai:Saci_1068 transcriptional regulator ArsR family.
  
  
 0.680
Pisl_0183
KEGG: sso:SSO2115 hypothetical protein.
       0.636
Pisl_1023
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: pai:PAE2309 ferric uptake regulator, putative.
  
  
 0.570
Pisl_1322
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pai:PAE1168 ABC transporter ATP-binding protein, putative.
 
    0.519
Pisl_2014
KEGG: pai:PAE0269 ABC-2 type transport system ATP-binding protein; TIGRFAM: daunorubicin resistance ABC transporter ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase.
 
    0.434
Pisl_0653
Transcriptional regulator, ArsR family; PFAM: regulatory protein, ArsR; Helix-turn-helix, type 11 domain protein; KEGG: pai:PAE0731 transcriptional regulatory protein, conjectural.
  
  
 0.433
Pisl_0903
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pai:PAE3066 ABC-2 type transport system ATP-binding protein.
 
    0.433
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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