Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Pisl_0189PFAM: Radical SAM domain protein; KEGG: pai:PAE2153 hypothetical protein. (353 aa)    
Predicted Functional Partners:
Pisl_0842
PFAM: Protein of unknown function DUF54; KEGG: pai:PAE2213 hypothetical protein.
  
     0.482
Pisl_0075
PFAM: extracellular solute-binding protein, family 1; KEGG: pai:PAE0061 extracellular solute binding protein, conjectural.
 
     0.440
Pisl_0028
KEGG: pai:PAE3657 hypothetical protein.
 
     0.434
srp19
Signal recognition particle, subunit SRP19 (srp19); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
  
   
 0.426
Pisl_0539
PFAM: THUMP domain protein; KEGG: pai:PAE3175 hypothetical protein.
  
     0.418
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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