Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_0191KEGG: sto:ST1045 hypothetical protein. (241 aa)    
Predicted Functional Partners:
Pisl_0192
PFAM: hydrogenase expression/synthesis, HypA; KEGG: sto:ST1046 hypothetical protein.
 
 
   0.977
Pisl_0190
Hypothetical protein.
       0.774
Pisl_0196
TIGRFAM: hydrogenase maturation protease; PFAM: peptidase M52, hydrogen uptake protein; KEGG: aeh:Mlg_2026 hydrogenase expression/formation protein.
       0.726
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
   
 
 0.716
Pisl_0194
Hypothetical protein.
       0.704
Pisl_0193
Transcriptional regulator, CopG family; KEGG: pab:PAB0960 putative nickel responsive regulator.
       0.700
Pisl_0197
PFAM: nickel-dependent hydrogenase, large subunit; KEGG: sma:SAV7367 putative cytochrome C3-like hydrogenase (NiFeSe) large chain.
       0.699
Pisl_0195
Hypothetical protein.
       0.682
Pisl_0335
PFAM: NADH dehydrogenase (ubiquinone), 30 kDa subunit; KEGG: pai:PAE2926 NADH-ubiquinone oxidoreductase subunit.
    
 0.609
Pisl_0327
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: pai:PAE1580 NADH-ubiquinone oxidoreductase subunit.
  
 
 0.586
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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