Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_0201Hypothetical protein. (207 aa)    
Predicted Functional Partners:
Pisl_0200
PFAM: Nickel-iron dehydrogenase small subunit, N-terminal domain protein; KEGG: fal:FRAAL2392 uptake hydrogenase small subunit precursor (hydrogenlyase) (membrane-bound hydrogenase small subunit).
     
 0.857
Pisl_0202
Hypothetical protein.
       0.800
Pisl_0199
Hypothetical protein.
       0.774
Pisl_0198
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: afu:AF0547 reductase, iron-sulfur binding subunit.
       0.620
Pisl_0197
PFAM: nickel-dependent hydrogenase, large subunit; KEGG: sma:SAV7367 putative cytochrome C3-like hydrogenase (NiFeSe) large chain.
     
 0.577
Pisl_0196
TIGRFAM: hydrogenase maturation protease; PFAM: peptidase M52, hydrogen uptake protein; KEGG: aeh:Mlg_2026 hydrogenase expression/formation protein.
     
 0.576
Pisl_0204
Beta-lactamase fold-like Zn-dependent hydrolase; KEGG: pai:PAE3189 hypothetical protein.
       0.567
Pisl_0203
TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: mth:MTH205 hydrogenase expression/formation protein HypE.
       0.560
Pisl_0194
Hypothetical protein.
       0.492
Pisl_0193
Transcriptional regulator, CopG family; KEGG: pab:PAB0960 putative nickel responsive regulator.
       0.482
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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