Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_0210PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mja:MJ1088 cobalt transport system ATP-binding protein. (223 aa)    
Predicted Functional Partners:
Pisl_0211
Hypothetical protein.
  
 0.999
Pisl_0213
PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; KEGG: afu:AF1843 cobalamin biosynthesis protein.
 
 
 0.992
Pisl_0212
Hypothetical protein.
  
 
 0.985
truA
Pseudouridylate synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family.
  
  
 0.768
Pisl_0287
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pai:PAE2893 spermidine/putrescine transport permease protein.
   
  
 0.697
Pisl_0215
PFAM: transport system permease protein; KEGG: afu:AF0431 iron (III) transport system permease protein.
     
 0.640
rpl2
LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
 
    0.639
Pisl_0214
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: chy:CHY_2191 iron compound ABC transporter, ATP-binding protein.
 
    
0.637
Pisl_0216
PFAM: periplasmic binding protein; KEGG: tte:TTE1869 ABC-type Fe3+-siderophores transport systems, periplasmic components.
     
 0.628
rpl14
LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
 
    0.627
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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