Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_0211Hypothetical protein. (194 aa)    
Predicted Functional Partners:
Pisl_0210
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mja:MJ1088 cobalt transport system ATP-binding protein.
  
 0.999
Pisl_0212
Hypothetical protein.
  
 
 0.995
Pisl_0213
PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; KEGG: afu:AF1843 cobalamin biosynthesis protein.
  
 
 0.993
truA
Pseudouridylate synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family.
  
  
 0.754
Pisl_0215
PFAM: transport system permease protein; KEGG: afu:AF0431 iron (III) transport system permease protein.
     
 0.635
Pisl_0214
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: chy:CHY_2191 iron compound ABC transporter, ATP-binding protein.
  
  
 0.610
Pisl_0216
PFAM: periplasmic binding protein; KEGG: tte:TTE1869 ABC-type Fe3+-siderophores transport systems, periplasmic components.
     
 0.598
Pisl_1368
PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; KEGG: pai:PAE0372 hypothetical protein; Belongs to the UPF0284 family.
  
  
 0.571
Pisl_0217
PFAM: protein of unknown function DUF364; KEGG: tko:TK0710 hypothetical protein.
  
    0.547
Pisl_1974
Transcriptional activator, TenA family; PFAM: TENA/THI-4 domain protein; KEGG: pai:PAE0170 conserved protein (tenA homolog).
  
  
 0.502
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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