Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_0213PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; KEGG: afu:AF1843 cobalamin biosynthesis protein. (202 aa)    
Predicted Functional Partners:
Pisl_0211
Hypothetical protein.
  
 
 0.993
Pisl_0210
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mja:MJ1088 cobalt transport system ATP-binding protein.
 
 
 0.992
Pisl_0212
Hypothetical protein.
  
 
 0.990
Pisl_0214
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: chy:CHY_2191 iron compound ABC transporter, ATP-binding protein.
 
  
 0.672
Pisl_0219
PFAM: formylmethanofuran dehydrogenase, subunit E region; KEGG: pab:PAB0675 molybdenum formylmethanofuran dehydrogenase subunit fmdE related.
 
    0.665
Pisl_0215
PFAM: transport system permease protein; KEGG: afu:AF0431 iron (III) transport system permease protein.
  
  
 0.632
Pisl_0216
PFAM: periplasmic binding protein; KEGG: tte:TTE1869 ABC-type Fe3+-siderophores transport systems, periplasmic components.
  
  
 0.602
Pisl_0217
PFAM: protein of unknown function DUF364; KEGG: tko:TK0710 hypothetical protein.
       0.526
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
     
 0.497
Pisl_0218
PFAM: AMP-dependent synthetase and ligase; KEGG: pai:PAE2867 acetyl-coenzyme A synthetase.
     
 0.493
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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